Oxidative Stress Markers and C-Reactive Protein Are Related to Severity of Heart Failure in Patients with Dilated Cardiomyopathy

Table 6

Spearman correlation between biomarkers.

	NT-ProBNP	Uric acid	CRP	SvO2	MnSOD	CuZnSOD	MDA
NTproBNP		0.167; NS	0.062; NS	−0.388; P < 0.001	0.194; P = 0.057	0.154; NS	−0.058; NS
SvO2	−0.388; P < 0.001	−0.192; NS	0.189; NS		−0.142; NS	0.102; NS	−0.062; NS
Uric acid	0.167; NS		0.188; NS	−0.192; NS	0.220; P < 0.05	0.017; NS	−0.021; NS
CRP	0.062; NS	−0.010; NS		0.189; NS	0.286; P < 0.05	0.364; P < 0.01	0.117; NS
MnSOD	0.194; P = 0.057	0.220; P < 0.05	0.286; P < 0.05	−0.142; NS		0.344; P < 0.001	0.080; NS
CuZnSOD	0.154; NS	0.017; NS	0.364; P < 0.01	0.102; NS	0.344; P < 0.001		−0.057; NS
MDA	−0.058; NS	−0.021; NS	0.117; NS	−0.062; NS	0.080; NS	−0.057; NS

NT-proBNP: N-terminal pro-B-type natriuretic peptide; CRP: C-reactive protein; SvO₂: mixed venous blood saturation; MnSOD: manganese superoxide dismutase; CuZnSOD: cooper-zinc superoxide dismutase; MDA: malondialdehyde.