Serum Matrix Metalloproteinase-3 as a Noninvasive Biomarker of Histological Synovitis for Diagnosis of Rheumatoid Arthritis
Figure 1
Representative immunohistochemical findings of synovial MMP-3 expression. (a) Mild synovial MMP-3 expression in lining cells in a discoid meniscus patient. (b) Moderate synovial MMP-3 expression in lining cells in an OA patient. (c) and (d) Intensive synovial MMP-3 expression in lining cells in a RA patient. (a, b, c) original magnification ×400; (d) original magnification ×1000. (e) Percentage of lining MMP3+ cells in OrthA, OA, and RA patients.
