AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18
Figure 2
Expression of AIM2 mRNA (a) and protein (b) in transiently transfected HGM cells. AIM2-siRNA#2 was identified as the most effective silencer. AIM2-siRNA was transiently transfected to HGM cells. AIM2-siRNA#1, siRNA#2, siRNA#3 resulted in reduction of expression of AIM2 detected by qRT-PCR with 0.5, 3.8 and 1.3 folds respectively (a). These changes were also noted at the translational level, as measured by Western blot (b). *indicates a significant difference compared with the control (). independent experiment RNA samples for each group.
