AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18
Figure 6
Downregulation of AIM2 had no influence on the expression of IL-6. HGM cells were divided into three groups: AIM2-siRNA and HBV DNA cotransfected group (group A), HBV DNA-transfected group without AIM2-siRNA (group B) and AIM2-siRNA, and empty plasmids cotransfected group (group C). The expression of IL-6 in group A detected by qRT-PCR had not changed compared with group B and group C (a). These similar changes were also noted at the translational level, as measured by Western blot (b). independent experiment RNA samples for each group.
