AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18

Table 2

AIM2 expression in HBV-GN and CGN.

Group	Tissue	𝑛	Age	Gender M (%)	AIM2				Positive rate (%)
					−	+	++	+++
HBV-GN	K	54	36.1±12.7	35 (64.8)	10	26	18	0; 0	81.4
CGN	K	25	38.2±15.5^∗	18 (72.0)**	24	1	0		4.0***

HBV-GN, hepatitis B virus-associated glomerulonephritis; CGN: chronic glomerulonephritis; K: kidney; M: male; ∗compared with HBV-GN, (𝑡=−1.909, 𝑃=0.06); ∗∗compared with HBV-GN, (𝜒²=0.400, 𝑃=0.527); ∗∗∗compared with HBV-GN, (𝜒²=38.746, 𝑃<0.01).