YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints

Figure 3

YKL-40 release from cultured OA cartilage correlated with MMP-1 and MMP-3. Cartilage samples from 97 OA patients were incubated for 42 h. Concentrations of YKL-40 released from OA cartilage into the culture media correlated positively to those of (a) MMP-1 and (b) MMP-3 (𝑟=0.34, 𝑃=0.001 and 𝑟=0.38, 𝑃<0.001, resp.).

(a)

(b)