Research Article

Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis

Figure 5

Kinetics of the extracellular catabolism of ATP (a) and ADP (b) in the LM-MP of the ileum of control and TNBS-injected rats. ATP and ADP (30 μM) were incubated at zero time (see Section 2). Collected samples were analysed by HPLC with UV detection to separate and quantify ATP (black), ADP (red), AMP (orange), ADO (green), INO (dark grey), and HX (light grey). Average results obtained in four experiments.
254640.fig.005a
(a)
254640.fig.005b
(b)