The Regulation of Inflammatory Mediators in Acute Kidney Injury via Exogenous Mesenchymal Stem Cells

Figure 1

Exogenous MSCs likely involve paracrine effects in regulating the inflammatory mediators to ameliorate AKI. They exert protective and reparative effects in the treatment of AKI by regulating inflammatory mediators like cytokines, chemokines, neutrophils, lymphocytes, NK cells, DCs, and macrophages. MSCs ultimately improve the kidney’s structure and function.