Serum Levels of LL-37 and Inflammatory Cytokines in Plaque and Guttate Psoriasis
Table 2
Statistical analysis results of serum levels of cytokines and LL-37 in patients with psoriasis and healthy controls.
Patients () Median (IQR), mean
Healthy controls () Median (IQR), mean
IL-1RA (pg/mL)
2.26 (0.00–7.18), 4.40
0.00 (0.00–1.62), 1.47
0.020*
IL-2 (pg/mL)
0.81 (0.59–1.25), 1.05
0.00 (0.00–0.92), 0.84
0.007*
IL-12 (pg/mL)
2.71 (0.00–4.80), 3.23
0.00 (0.00–1.36), 1.33
0.071
IL-17A (pg/mL)
0.31 (0.00–1.37), 1.59
0.00 (0.00–2.75), 1.52
0.936
IL-22 (pg/mL)
0.11 (0.09–0.18), 0.15
0.10 (0.10–0.13), 0.11
0.625
IL-23 (pg/mL)
1.57 (1.44–2.00), 1.99
0.95 (0.45–1.24), 1.02
<0.001*
IFN-γ (pg/mL)
2.94 (2.46–5.18), 4.53
0.50 (0.00–2.06), 1.34
<0.001*
LL-37 (ng/mL)
11.78 (9.75–16.90), 13.46
8.73 (7.73–11.60), 9.43
0.011*
IL: interleukin; IL-1RA: IL-1 receptor antagonist; IFN: interferon; IQR: interquartile range. aMann-Whitney U test between healthy controls and patients with psoriasis.
*denotes statistically significant difference at .
