Multitracer Stable Isotope Quantification of Arginase and Nitric Oxide Synthase Activity in a Mouse Model of Pseudomonas Lung Infection

Figure 1

Expression of inducible nitric oxide synthase (NOS2) and the arginase isoform types I (ARG1) and II (ARG2) normalized to GAPDH, respectively, in lung of Pseudomonas aeruginosa infected mice and naïve control ( per group). Infection resulted in a significant increase in protein expression of all three enzymes (, ).