A Natural Flavonoid Glucoside, Icariin, Regulates Th17 and Alleviates Rheumatoid Arthritis in a Murine Model

Figure 6

Icariin inhibited STAT3 activation in T cells in vivo and in vitro. (a) Synovial p-STAT3 protein level was analyzed using Western blotting. (b) Naive T cells from mice were treated with 3 μM icariin for 24 hours, followed by stimulation of IL-6 (25 ng/mL) for 30 min. Protein levels were assessed using Western blot. versus all other groups, .

(a)  

(b)