Research Article

Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial

Table 2

Cardiovascular parameters at baseline (J0) and after 12 weeks (M3) of placebo or statin treatment.

J0M3Change M3 − J0 Difference in change (95% CI)

PAT
 Placebo ()0.008 (−0.29; 0.28)
 Statin ()
Carotid-to-femoral PWV (m/s)
 Placebo ()0.54 (−0.45; 1.52)
 Statin ()
Right carotid IMT (m)
 Placebo ()0.02 (−70.38; 70.35)
 Statin ()
Left carotid IMT (m)
 Placebo ()17.42 (−45.98; 80.81)
 Statin ()
Mean carotid IMT (m)
 Placebo ()5.34 (−51.34; 62.02)
 Statin ()
Right carotid luminal diameter (m)
 Placebo ()83 (−305; 472)
 Statin ()$
Left carotid luminal diameter (m)
 Placebo ()−73 (−360; 215)
 Statin ()

Data are mean ± SD or percentage. PAT, peripheral arterial tone; PWV, pulse wave velocity; IMT, intima-media thickness. Analysis of data by repeated measure two-way ANOVA, followed by a Bonferroni post hoc test when necessary.
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