Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial
Table 2
Cardiovascular parameters at baseline (J0) and after 12 weeks (M3) of placebo or statin treatment.
J0
M3
Change M3 − J0
Difference in change (95% CI)
PAT
Placebo ()
0.008 (−0.29; 0.28)
Statin ()
Carotid-to-femoral PWV (m/s)
Placebo ()
0.54 (−0.45; 1.52)
Statin ()
Right carotid IMT (m)
Placebo ()
0.02 (−70.38; 70.35)
Statin ()
Left carotid IMT (m)
Placebo ()
17.42 (−45.98; 80.81)
Statin ()
Mean carotid IMT (m)
Placebo ()
5.34 (−51.34; 62.02)
Statin ()
Right carotid luminal diameter (m)
Placebo ()
83 (−305; 472)
Statin ()
$
Left carotid luminal diameter (m)
Placebo ()
−73 (−360; 215)
Statin ()
Data are mean ± SD or percentage. PAT, peripheral arterial tone; PWV, pulse wave velocity; IMT, intima-media thickness. Analysis of data by repeated measure two-way ANOVA, followed by a Bonferroni post hoc test when necessary. $ for value visit.