Adipokines as Potential Biomarkers in Rheumatoid Arthritis

Figure 1

Role of adipokines on RA effector cells. The role of different adipokines on RA target cells is illustrated in the figure. WAT: white adipose tissue, SAA3: serum amyloid A3, FLS: fibroblast-like synoviocytes, AC: articular chondrocytes, PMN: neutrophils, MMP: metalloprotease, COX-2: cyclooxygenase 2, ROS: reactive oxygen species, iNOS: inducible nitric oxide synthase, CC-CK: CC-chemokines, TG2: transglutaminase 2, and TERA: transitional endoplasmic reticulum ATPase.