Adipose-Derived Stem Cells Ameliorate Allergic Airway Inflammation by Inducing Regulatory T Cells in a Mouse Model of Asthma

Figure 6

Effects of adipose-derived stem cells (ASCs) on Tregs, IL-4 or IFN-γ producing T cells, and gene expression of IDO and TGF-β. (a) ASCs treatment significantly increased the frequency of Tregs. IL-4⁺CD4⁺ T cells (b) were significantly decreased, but IFN-γ ⁺CD4⁺ T cells (c) were significantly increased by ASCs treatment. (d) The gene expression levels of IDO and TGF-β and PGE₂ levels were significantly increased by ASCs treatment.

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