Proteomic Analysis of Lung Tissue in a Rat Acute Lung Injury Model: Identification of PRDX1 as a Promoter of Inflammation

Table 2

The classification of differential proteins in ALI lung tissue with the comparison of control group.

Protein name	Accession number	Protein MW (Da)	Regulation	Fold change
(A) Metabolism protein
Glyceraldehyde-3-phosphate dehydrogenase	gi|8393418	35805.2	Up	2.13
Phosphoglycerate kinase 1	gi|40254752	44510	Up	2.32
Aldehyde dehydrogenase, mitochondrial	gi|45737866	55566.2	Up	2.07
Nucleoside diphosphate kinase B	gi|55926145	17271.9	Up	2.03
Malate dehydrogenase	gi|37590235	36461	Down	2.31
Aldolase A	gi|202837	39235.3	Up	2.20
(B) Antioxidant
Superoxide dismutase2	gi|8394331	24658.6	Up	2.57
Peroxiredoxin 1	gi|16923958	22095.3	Up	4.79
Glutathione S-transferase alpha-4	gi|157820217	25493.4	Down	2.88
(C) Binding proteins
Lectin, galactose binding, soluble 5	gi|6981154	16186	Down	2.86
Transthyretin	gi|20663827	13589.8	Down	2.70
Apolipoprotein E	gi|37805241	35741.4	Down	2.44
Calreticulin	gi|253851	29142.4	Up	2.40
Selenium-binding protein 1	gi|18266692	52498.4	Down	2.73
Vitamin-D binding protein	gi|203941	53482	Up	2.77
Haptoglobin	gi|60097941	38538.5	Up	3.1
(D) Signal transduction
Rho-associated protein kinase 1	gi|13592049	159526.6	Down	2.72
Translationally controlled tumor protein	gi|6678437	19449.6	Up	2.94