Interleukin-1 Receptors Are Differentially Expressed in Normal and Psoriatic T Cells

Figure 3

Expression of IL-1R1 and IL-1R2 proteins in healthy control and psoriatic CD4⁺ cells. Healthy and psoriatic CD4⁺ cells were isolated and labelled as described. Cell surface IL-1R1 (a) and IL-1R2 (b) proteins were stained with biotinylated primary antibodies and PE/APC-conjugated streptavidin. Percentage of positive cells of CD4⁺ Treg, TM, and TN subpopulations from individual samples is depicted (𝑛=4). Circles represent resting cells (CON), whereas CD3/CD28 stimulated cells (ACT) are indicated as triangles. Mean fluorescence intensities (MFI) of IL-1R1 (c) and IL-1R2 (d) positive cells are shown. *𝑃<0.05, **𝑃<0.01.

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