Association between Peak Neutrophil Count, Clopidogrel Loading Dose, and Left Ventricular Systolic Function in Patients with Primary Percutaneous Coronary Intervention
Table 1
Baseline characteristics.
Variable
Low clopidogrel loading dose (300–450 mg) ()
High clopidogrel loading dose (600 mg) ()
P value
Age (yrs)
0.84
Male sex (%)
79.9
82.7
0.65
Hypertension (%)
52.1
51.0
0.91
Diabetes mellitus (%)
35.9
28.6
0.21
Hypercholesterolemia (%)
37.5
33.7
0.54
Current smoking (%)
48.3
55.1
0.29
Family history of CAD ()
14.7
15.3
0.87
Body mass index (kg/m2)
0.45
Anterior infarction (%)
51.9
41.8
0.10
Prior angina (%)
65.3
55.1
0.07
Systolic blood pressure (mm Hg)
0.23
Diastolic blood pressure (mm Hg)
0.13
Time to admission (h)
0.95
ST-segment resolution 50% within 120 minutes after PPCI (%)
87.6
87.6
1.00
Corrected TIMI frame count
0.36
Hemoglobin (g/L)
0.58
hs-CRP (mg/L)*
9.11 (3.23, 23.35)
4.20 (1.79, 17.97)
0.03
Creatinine (mol/L)
0.83
Serum glucose (mmol/L)
0.13
Total cholesterol (mmol/L)
0.58
Triglyceride (mmol/L)
0.15
HDL-C (mmol/L)
0.06
LDL-C (mmol/L)
0.33
IIb/IIIa inhibitors
32.0
28.6
0.70
Values represent mean SD or the percent of the patients. Values represent median with 25 and 75 percentiles. Note: CAD: coronary artery disease; PPCI: primary percutaneous coronary intervention; hs-CRP: high-sensitive C-reactive protein; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol.