Association between Peak Neutrophil Count, Clopidogrel Loading Dose, and Left Ventricular Systolic Function in Patients with Primary Percutaneous Coronary Intervention

Table 1

Baseline characteristics.

Variable	Low clopidogrel loading dose (300–450 mg); (𝑛=259)	High clopidogrel loading dose (600 mg); (𝑛=98)	P value
Age (yrs)	61.4±13.3	61.1±12.7	0.84
Male sex (%)	79.9	82.7	0.65
Hypertension (%)	52.1	51.0	0.91
Diabetes mellitus (%)	35.9	28.6	0.21
Hypercholesterolemia (%)	37.5	33.7	0.54
Current smoking (%)	48.3	55.1	0.29
Family history of CAD (%)	14.7	15.3	0.87
Body mass index (kg/m^2)	26.1±4.2	25.5±3.8	0.45
Anterior infarction (%)	51.9	41.8	0.10
Prior angina (%)	65.3	55.1	0.07
Systolic blood pressure (mm Hg)	134.3±25.9	138.8±31.3	0.23
Diastolic blood pressure (mm Hg)	76.8±16.6	80.9±19.7	0.13
Time to admission (h)	4.8±3.7	4.9±4.5	0.95
ST-segment resolution ≥50% within 120 minutes after PPCI (%)	87.6	87.6	1.00
Corrected TIMI frame count	32.1±19.0	30.0±18.5	0.36
Hemoglobin (g/L)	144.3±19.1	145.6±16.4	0.58
hs-CRP (mg/L)*	9.11 (3.23, 23.35)	4.20 (1.79, 17.97)	0.03
Creatinine (𝜇mol/L)	86.7±21.0	87.3±21.5	0.83
Serum glucose (mmol/L)	6.74±3.01	6.20±2.37	0.13
Total cholesterol (mmol/L)	4.69±1.03	4.63±0.83	0.58
Triglyceride (mmol/L)	1.73±0.92	1.91±1.19	0.15
HDL-C (mmol/L)	0.95±0.24	0.90±0.20	0.06
LDL-C (mmol/L)	3.02±0.90	2.92±0.73	0.33
IIb/IIIa inhibitors	32.0	28.6	0.70

Values represent mean ± SD or the percent of the patients. ∗Values represent median with 25 and 75 percentiles.
Note: CAD: coronary artery disease; PPCI: primary percutaneous coronary intervention; hs-CRP: high-sensitive C-reactive protein; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol.