Study of the Correlations among Some Parameters of the Oxidative Status, Gelatinases, and Their Inhibitors in a Group of Subjects with Metabolic Syndrome
Table 2
Medians (interquartile ranges) of gelatinase and inhibitor plasma concentrations in normal controls, in the whole group of MS patients, and in the two subgroups, respectively, with and without diabetes mellitus.
Control subjects
All MS patients
Diabetic MS patients
Nondiabetic MS patients
TBARS (nmol/mL)
5.71 (2.28)
8.83 (0.70)
8.99 (0.71)
8.73 (0.665)
PC (nmol/mg prot.)
0.470 (0.125)
0.880 (0.240)
0.880 (0.240)
0.880 (0.220)
TAS (mmol/L)
0.910 (0.330)
0.880 (0.300)
0.910 (0.150)
0.720 (0.395)
(μmol/L)
28.05 (24.65)
74.80 (26.52)
77.10 (24.20)
67.70 (43.92)
MMP-2 (ng/mL)
29.19 (6.07)
44.50 (10.46)
47.84 (10.76)
39.69 (9.75)
MMP-9 (ng/mL)
53.17 (6.57)
105.6 (36.15)
127.3 (28.7)
91.50 (11.61)
TIMP-1 (ng/mL)
30.99 (2.63)
73.47 (10.31)
75.66 (8.65)
68.45 (9.35)
TIMP-2 (ng/mL)
87.27 (6.28)
98.77 (14.38)
99.79 (12.86)
95.21 (15.32)
MMP-2/TIMP-2
0.354 (0.080)
0.449 (0.130)
0.460 (0.104)
0.391 (0.141)
MMP-9/TIMP-1
1.720 (0.150)
1.480 (0.345)
1.658 (0.339)
1.347 (0.298)
, , and versus control subjects (Mann-Whitney test). and versus diabetic MS patients.
