Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

Figure 1

HbA_1c levels in control nondiabetic ZDF (+/+) and diabetic ZDF (fa/fa) rats nontreated and treated with 10 mg/kg/day sitagliptin for 6 weeks, at 26 weeks of age. Data are expressed as mean ± SEM (𝑛≥6 per group); ^∗∗∗𝑃<0.001 significantly different from control; ^##𝑃<0.01 significantly different from diabetic.