Review Article

Major Histocompatibility Complex I Mediates Immunological Tolerance of the Trophoblast during Pregnancy and May Mediate Rejection during Parturition

Table 3

Definitions of receptors and molecules mentioned in the paper.

Name Full namePresenting cellFunctionSynonyms

KIR2DKiller cell immunoglobulin-like receptorNK cellsSpecific for HLA-C; inhibitory effect on NK cellCD158 and 2DL3

KIR2DL4Killer cell immunoglobulin-like receptorNK cellsBinds MHC I and activates NK cellsCD158D, KIR103, 2DL4, and KIR103AS

LIR-1 Leukocytes immunoglobulin-like receptor 1Immune cellsBinds MHC I and inhibits stimulationCD85, ILT2, MIR7, LILRB1, and Ig-like receptor 1

LIR-2Leukocytes immunoglobulin-like receptor 2Immune cellsBinds MHC I and inhibits stimulationCD58D, ILT4, MIR-10, 2

CD80 CD80 moleculeMacrophages and activated B lymphocytesInvolved in costimulatory signal for T-lymphocytes activation and works together with CD86CD28LG, CD28LG1, and LAB7

CD86CD86 moleculeAntigen presenting cellsInvolved in costimulatory signal for T-lymphocytes activation and works together with CD80CD28LG2, LAB72, B7-2, and B70

CD9CD9 moleculeCells exosomes Mediates signal transduction events for regulation of cell development, activation, growth, and motilityMIC3, BTCC-1, DRAP-27, TSPAN-29, and MRP-1