Elevated Serum IgG4 Defines Specific Clinical Phenotype of Rheumatoid Arthritis

Figure 3

Correlation of IgG4-positive plasma cells with serum IgG4 and inflammatory infiltration in synovium of 46 RA patients. Spearman’s rank order correlation test showed significant correlation of IgG4-positive plasma cells with serum IgG4 (a), CD3+ (c), CD20+ (d), and CD38+ cells (e). Patients with severe inflammatory infiltration () had higher IgG4-positive plasma cells than those with mild inflammatory infiltration in synovium () (b).

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