Paeonol Attenuates Cigarette Smoke-Induced Lung Inflammation by Inhibiting ROS-Sensitive Inflammatory Signaling

Figure 2

Paeonol (Pae) suppresses cigarette smoke- (CS-) induced increases in proinflammatory chemokines and cytokines in bronchoalveolar lavage fluid (BALF) sampled from mice. Levels of macrophage inflammatory protein 2 (MIP-2; (a)), monocyte chemoattractant protein-1 (MCP-1; (b)), keratinocyte chemoattractant (KC; (c)), and interleukin-1β (IL-1β; (d)) in BALF were analyzed by ELISA. Data in each group are mean ± SEM from 7 mice. ^∗𝑃<0.05 versus the air-exposure group; ^#𝑃<0.05 versus the CS-exposure group with vehicle treatment. See legend of Figure 1 for detailed information on each study group.

(a)

(b)

(c)

(d)