Paeonol Attenuates Cigarette Smoke-Induced Lung Inflammation by Inhibiting ROS-Sensitive Inflammatory Signaling

Figure 4

Paeonol (Pae) suppresses cigarette smoke- (CS-) induced increases in expression of inflammatory target proteins ((a), (b)) and oxidative stress-related proteins (c) in lung tissues samples from mice. (a) Intercellular adhesion molecule 1 (ICAM-1); (b) vascular cell adhesion molecule 1 (VCAM-1); (c) 4-hydroxynonenal (4-HNE) modified proteins (a biomarker of oxidative stress). Protein levels in the lung tissues were analyzed by Western blotting. Data in each group are mean ± SEM from 7 mice. ^∗𝑃<0.05 versus the air-exposure group; ^#𝑃<0.05 versus the CS-exposure group with vehicle treatment. See legend of Figure 1 for detailed information on each study group.

(a)

(b)

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