A Role of Lipid Metabolism during Cumulus-Oocyte Complex Maturation: Impact of Lipid Modulators to Improve Embryo Production

Figure 2

A model for lipid droplets (LD) biogenesis ((a), (b)) during pig oocyte (c) maturation: (a), de novo synthesis of LD in endoplasmic reticulum membrane and (b) LD coalescence process, with lipid trafficking mediated by snare (Snare P, orange batons) and caveolins (orange coiled lines) proteins (based on a study by Suzuki et al. [18]). Perilipins proteins (TIP47 green batons) involved in the mechanism of lipolysis regulation. (c) Pig oocyte with 24 hours of in vitro maturation. Scale bar 50 μm. CE, cholesterol esters; ER, endoplasmic reticulum; TGA, triacylglycerols.