Efficiency of Double Layered Microencapsulated Probiotic to Modulate ProInflammatory Molecular Markers for the Management of Alcoholic Liver Disease

Table 4

Bile salt tolerance of L. plantarum (log₁₀ cfu) in alginate (AL) and alginate coated chitosan beads (AL-CA) (𝑛=6).

	Initial count	1 hr	2 hr	3 hr	4 hr
Unencapsulated probiotic	8.92±1.23	7.97±0.5	6.91±0.89	6.85±1.54	6.57±0.77
AL beads	8.74±0.37	8.25±0.18	7.85±0.54	7.74±0.16	7.55±0.67^a
AL-CA beads	8.88±0.65	8.74±0.45	7.95±0.14	7.62±0.49	7.95±0.87^b,c

All values are represented as mean ± standard deviation in. ^a𝑃<0.05 versus unencapsulated probiotic; ^b𝑃<0.05 versus unencapsulated probiotic; ^c𝑃<0.05 versus AL beads after 4 hours of incubation in 0.3% bile salts.