The Macrophage Inflammatory Proteins MIP1 (CCL3) and MIP2 (CXCL2) in Implant-Associated Osteomyelitis: Linking Inflammation to Bone Degradation
Figure 3
CXCL2 and CCL3 synthesis by cultivated osteoblast. (a) Gene expression of CXCL2 and CCL3 following stimulation of osteoblasts with LTA (1 μg/mL) for the time indicated. (b) Release of CXCL2 into the supernatant determined following stimulation of osteoblasts with either S. epidermidis or S. aureus in three doses (given as ratio of bacteria per osteoblasts) (one of three independent experiments giving essentially similar results is shown).
