Anti-Inflammatory Effect of IL-37b in Children with Allergic Rhinitis
Figure 5
The regulation of Th2 cytokines (IL-4, IL-5, and IL-13) by IL-37b in PBMC in a dose and time dependent manner. (a) IL-4 expression by PBMC after stimulated with different concentration of IL-37b with or without SB203580 and LY294002; (b) IL-5 expression by PBMC after stimulated with different concentration of IL-37b with or without SB203580 and LY294002; (c) IL-13 expression by PBMC after stimulated with different concentration of IL-37b with or without SB203580 and LY294002; (d) IL-37b decreased IL-4 expression by PBMC in a time dependent manner; (e) IL-37b decreased IL-5 expression by PBMC in a time dependent manner; (f) IL-37b decreased IL-13 expression by PBMC in a time dependent manner. , comparing the two groups.
