Research Article

Early Effects of a Hypocaloric, Mediterranean Diet on Laboratory Parameters in Obese Individuals

Table 3

Significant variations of anthropometric, clinical, and biochemical features of obese patients after one month of calorie restriction.

Baseline1 month

Weight (Kg)91 (82–112)87 (83–101)<0.001
BMI (Kg/m2)37 (32–39)36 (31–38)<0.001
Basal insulin (µU/mL)18.0 (13.0–27.0)15.0 (10.0–20.0)0.011
HOMA-IR 4.0 (3.0–6.0)4.0 (2.0–5.0)0.006
Leptin (ng/mL)46.0 (31.0–70.0)35.0 (22.0–46.0)<0.001
Resistin (ng/mL)5.0 (4.0–6.0)5.0 (5.0–7.0)0.017
Total cholesterol (mg/dL)199 (172–225)190 (148–220)0.047
EGF (pg/mL)86 (68–130)114 (84–144)0.018

Nonparametric Wilcoxon test has been used for comparisons at two times. All variables are expressed as median and quartiles.