HMGB1 Localization during Experimental Periodontitis
Figure 2
(a) Stereometric analysis of the inflammatory cells. Representative histologic section shows the 3 areas used for analysis. Graphs show average ± standard deviation of scores obtained in the LPS- and ligature-induced periodontal disease models. The LPS model is associated with a sustained inflammatory reaction, while the ligature model presented higher density of cellular infiltrate at 7 days and a decrease on the severity of inflammation at 30 days. (b) and (c) HMGB1 mRNA and protein expression assessed by qPCR (b) and Western blot (c) during the course of LPS- and ligature-induced periodontal disease. *Significant difference compared to control ().
