Regulation of NAMPT in Human Gingival Fibroblasts and Biopsies
Figure 1
Expression of NAMPT and other adipokines in HGF. (a) Upregulation of NAMPT mRNA expression by IL-1β, P. gingivalis (Pg), and F. nucleatum (Fn) in HGF from 8 donors at 12 h and 24 h. (b) Stimulation of NAMPT mRNA expression by various concentrations (0.2, 1.0, and 5.0 ng/mL) of IL-1β in HGF from 3 donors at 12 h. (c) Stimulation of NAMPT mRNA expression by various doses (OD: 0.025, 0.050, and 0.100) of F. nucleatum in HGF from 3 donors at 12 h. (d) Expression of adiponectin, leptin, and resistin in IL-1β-, P. gingivalis- (Pg-), and F. nucleatum- (Fn-) treated HGF from 6 donors. Mean ± SEM; *significantly () different from control.
