Myocardial Gene Expression of T-bet, GATA-3, Ror-𝜸t, FoxP3, and Hallmark Cytokines in Chronic Chagas Disease Cardiomyopathy: An Essentially Unopposed T_H1-Type Response

Table 2

Correlation of mRNA expression of T cell lineage-associated molecules against each other and versus LVDD on heart tissue from CCC patients using Spearman’s rank correlation.

mRNA expression	𝑃	𝑟
T-bet versus LVDD	0.043	0.546
T-bet versus Foxp3	0.047	0.538
T-bet versus CTLA-4	0.0001	0.903
IFN-𝛾 versus Foxp3	0.004	0.714
IFN-𝛾 versus CTLA-4	0.004	0.710
IL-18 versus T-bet	0.045	0.543
IL-18 versus IFN-𝛾	0.002	0.749
IL-18 versus Foxp3	0.009	0.670
IL-18 versus CTLA-4	0.007	0.648
Foxp3 versus CTLA-4	0.001	0.771