Research Article
The Functional Polymorphisms of miR-146a Are Associated with Susceptibility to Severe Sepsis in the Chinese Population
Table 1
Clinical characteristics of sepsis cases and healthy controls.
| Characteristics | Cases ) | Controls () | value | (%) | (%) |
| Age (years) | | | 0.174 | Male/female, | 153/73 | 140/66 | 0.954 | Organ dysfunction | | | | One, (%) | 37 (16.4) | N.A | | Two, (%) | 72 (31.9) | N.A | | Three or above, (%) | 83 (36.7) | N.A | | Sepsis status | | | | Sepsis, (%) | 34 (15.0) | N.A | | Septic shock, (%) | 65 (28.8) | N.A | | Severe sepsis, (%) | 127 (56.2) | N.A | | Source of infection, (%) | | | | Respiratory tract infection | 181 (80.1) | N.A | | Primary bloodstream infection | 90 (39.8) | N.A | | Wound infection | 23 (10.2) | N.A | | Abdominal infection | 84 (37.2) | N.A | | Urinary tract infection | 7 (3.1) | N.A | | Catheter-associated infection | 31 (13.7) | N.A | | Others | 22 (9.7) | N.A | | Pathogens, (%) (positive blood cultures) | | | | Gram-negative | 82 (36.3) | N.A | | Gram-positive | 40 (17.7) | N.A | | Mixed Gram-negative and -positive | 78 (34.5) | N.A | | Fungus | 47 (20.8) | N.A | | Negative blood cultures | 12 (5.3) | N.A | | APACHE II score | | N.A | | 28-day mortality, (%) | 97 (42.9) | N.A | |
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N.A: not applicable; APACHE II: Acute Physiology and Chronic Health Evaluation II.
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