Antagonizing Arachidonic Acid-Derived Eicosanoids Reduces Inflammatory Th17 and Th1 Cell-Mediated Inflammation and Colitis Severity
Figure 5
Distal colon histological injury/damage scores assessed in Wt, Het, and Null Fads1 TNBS-treated mice (–10/genotype) in a blinded manner by a board-certified pathologist (B. Weeks). ((a)–(c)) Representative images (100x magnification, scale bar = 100 μm) of Wt, Het, and Null Fads1 TNBS-treated distal colons, respectively. (d) Distal colon injury scores (0–3). Data were analyzed using the Kruskal-Wallis test () followed by Wilcoxon two-sample testing. Median values are shown and significant differences between genotypes are marked by an asterisk ().
