Antagonizing Arachidonic Acid-Derived Eicosanoids Reduces Inflammatory Th17 and Th1 Cell-Mediated Inflammation and Colitis Severity
Figure 6
Percentage of splenic CD4+ T cell subsets in Wt, Het, and Null Fads1 TNBS-treated mice (black bars, –9 mice/genotype) and saline controls (grey bars, -4 mice/genotype). (a) Th17 cells (CD4+ IL-17A+), (b) Th1 cells (CD4+ IFNγ +), (c) Th2 cells (CD4+ IL-4+), and (d) Tregs (CD4+ Foxp3+). Data were analyzed by two-way ANOVA (main effects: genotype and treatment). Bars represent means ± SEM. Bars not sharing a symbol differ ().
