Research Article

Trypanosoma cruzi Infection in Genetically Selected Mouse Lines: Genetic Linkage with Quantitative Trait Locus Controlling Antibody Response

Figure 5

IFN-γ (a) and nitric oxide (NO) (b) production by lymph node (a) and peritoneal cells (b) during the acute phase of infection with 102 T. cruzi parasites (CL strain) in outbred HIII and LIII mice. Cells were stimulated in culture with ConA (2.5 μg/mL) for 48 h. Results are expressed as the means ± SE of each group (). Significant differences between infected and control mice (X) or between lines (∗) evaluated by ANOVA followed by Tukey multiple comparison tests are indicated when .
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(a)
952857.fig.005b
(b)