Involvement of Proteasome and Macrophages M2 in the Protection Afforded by Telmisartan against the Acute Myocardial Infarction in Zucker Diabetic Fatty Rats with Metabolic Syndrome

Figure 4

Immunoblotting for the macrophages CD206, CD11c, and MHCII in cardiac tissue of ZDF rats. (a) Expression of mannose receptor (CD206) characterizing M2 macrophage phenotype. (b, c) Expression of Integrin Alpha X/CD11c and of the major histocompatibility complex (MHC) class II characteristic M1 macrophage phenotype. Values ​​are reported as mean ± standard error. ^∗𝑃<0.05 and ^∗∗𝑃<0.01 versus control. I/R (ischemia/reperfusion); tel 7 (telmisartan 7 mg/kg); tel 12 (telmisartan 12 mg/kg).

(a)

(b)

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