P2Y₁₂ Receptor on the Verge of a Neuroinflammatory Breakdown

Figure 7

Draw of microglial marker expression as a function of activation. Branched microglia are represented in blue and activated microglia in red. Iba1 [22], CD11b, and MHC II are mostly expressed in microglia throughout the different morphological states and their expression increases during activation (light blue to red color). P2Y₁₂ c-ter (light blue) and CD68 (red) are expressed, respectively, in branched or roundish/activated microglia.