Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits

<table>Analysis of coronary atherosclerosis. The heart was cut into 7 blocks, and blocks I and II containing left and right coronary trunks were sectioned in 500 <i>μ</i>m intervals (3 sections from each block) and stained with EVG. Coronary stenosis (lesion area/total lumen area × 100(%) was measured and is expressed as percentage. LCA indicates left coronary artery trunks; and RCA, right coronary artery trunks.</table>

Mediators of Inflammation

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Figure 10

Figure 10: Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits 