Autophagy Upregulation and Apoptosis Downregulation in DAHP and Triptolide Treated Cerebral Ischemia

Figure 3

The expression level of Beclin-1 was detected by immunochemistry and western blot. Both immunochemistry and western blot staining present an increasing tendency in Beclin-1 expression in DAHP and TP and a decrease in MCAO. (a) There is no obvious difference between vehicle and control. The image shows a decrease in MCAO, while DAHP and TP were more or less back to the same level as vehicle and control. (b) There has been significance among mean changes in Beclin-1, as compared with vehicle and normal control; MCAO has the trend to descend. (c) The mean change in Beclin-1 expression detected by immunochemistry has significance, also owning comparison among MCAO, DAHP, and TP. (d) The immunochemistry staining shows similar changes in Beclin-1 expression in each group as in (a). Bar = 100 μm.

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