Autophagy Upregulation and Apoptosis Downregulation in DAHP and Triptolide Treated Cerebral Ischemia

Figure 4

Western blot was conducted to detect the expression level of Mcl-1 among each group, which is consistent with Beclin-1 expression. Western blot staining presents an increasing tendency in Mcl-1 in DAHP and TP but a decrease in MCAO. (a) Compared with vehicle and control, the image shows a slight decreasing in MCAO, and the DAHP and TP were very likely to be the same level. (b) The mean change in Mcl-1 was significant. MCAO has a decrease, while DAHP and TP attenuated the tendency. DAHP and TP can be compared with normal control with a small fluctuation of 5%–10%. Values are the means ± SEMs. ; ; ; n.s.: no significance.

(a)

(b)