iNOS Activity Modulates Inflammation, Angiogenesis, and Tissue Fibrosis in Polyether-Polyurethane Synthetic Implants

Figure 4

Enhanced collagen deposition in implants from iNOS^−/− mice. Representative photomicrographs of Picrosirius-red-stained sections (a) for collagen assessment under polarized light microscopy. Morphometric analysis of collagen content (b). The sponges were collected at day 14 after implantation. Values were represented as means (±SEM) from groups of 8 animals each. versus WT group (Student’s -test). Bar 50 μm.

(a)

(b)