ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF-α and NF-κB P65

Figure 1

Articular cartilage is degraded in ONFH patients, and the degradation is associated with the pathogenesis of ONFH. (a) Representative X-ray images of three groups. (b) H&E staining of femur articular cartilage. Samples from femur articular cartilage of FNF patients and ONFH patients at different stages, as indicated, were harvested. (c) Safranin-O staining of femur articular cartilage. The cartilage staining was reduced with the progression of ONFH. Representation sections are shown. (d) Mankin score of femur articular cartilage from each group. Group II and group III got statistically significant higher score than group I (, ). Group III got statistically significant higher scores than group II (^#, ^##).

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