Clinical Study

Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One-Lung Ventilation in Patients

Table 1

General characteristics and preoperative data.

DISO groupNISO group
()()

Age (yr) 55 ± 1256 ± 11
Gender (M/F) 17/816/8
Weight (kg) 61 ± 1260 ± 14
Height (cm) 167 ± 5165 ± 7
ASA physical status (I/II) 3/222/22
Preoperative blood gas
 pH7.42 ± 0.027.41 ± 0.03
 PaO2 (mmHg) 79.7 ± 13.779.5 ± 14.1
 PaCO2 (mmHg) 35.5 ± 3.734.9 ± 4.1
 Hb (g/L) 119.5 ± 13.8120.5 ± 12.5
Preoperative pulmonary function
 FEV1 (%) 79 ± 1781 ± 16
 FVC (%) 86 ± 1487 ± 11
 FEV1/FVC (%) 83 ± 1380 ± 10

FEV1: forced expiratory volume in one second; FVC: forced vital capacity; Hb: hemoglobin. There is no statistic difference between groups.