Clinical Study

Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One-Lung Ventilation in Patients

Table 3

Changes in MDA level, SOD activity, and NO concentration in DISO group and NISO group ().

Group TLV-15 min OLV-30 min

MDA (umol/L) DISO ( = 25)16.9 ± 1.717.5 ± 1.2b
NISO ( = 24)18.3 ± 1.721.0 ± 1.7a

SOD (ug/mL) DISO ( = 25)1.9 ± 0.21.8 ± 0.3b
NISO ( = 24)1.9 ± 0.11.6 ± 0.2a

NO (ug/mL) DISO ( = 25)1.9 ± 0.32.3 ± 0.3a;b
NISO ( = 24)1.9 ± 0.41.8 ± 0.1

< 0.05 versus TLV-15 min; < 0.05 versus NISO group.