Ouabain Modulates Zymosan-Induced Peritonitis in Mice

Figure 1

Ouabain decreases plasma extravasation induced by zymosan. Swiss mice () were pretreated with 0.56 mg/kg of ouabain (i.p.) or PBS for 3 consecutive days. One hour after the last dose of treatment, animals were stimulated with zymosan (i.p.). The results were expressed as absorbance for the Evans blue dye present in the peritoneal exudate. Results were expressed as mean ± SEM and analyzed by Graphpad Prism using ANOVA with Tukey’s posttest, where all groups were compared. versus PBS group and versus zymosan group.