Ouabain Modulates Zymosan-Induced Peritonitis in Mice

Figure 2

Total cell number in the peritoneal cavity 4 and 24 h after injection with zymosan. Swiss mice () were treated with 0.56 mg/kg of ouabain (i.p.) or PBS for 3 consecutive days. One hour after the last dose of treatment, animals were stimulated with zymosan (i.p.). Four and 24 hours after challenge with zymosan, peritoneal exudate was collected and total leukocyte counts were performed. Results were expressed as mean ± SEM and analyzed by Graphpad Prism using ANOVA with Tukey’s posttest, where all groups were compared. versus PBS group and versus zymosan group.