Fas/FasL Pathway Participates in Regulation of Antiviral and Inflammatory Response during Mousepox Infection of Lungs

Figure 3

Lack of Fas or FasL leads to disturbances in antiviral immune response. Total counts of NK cells (a) NK/IFN-γ+ cells (b), CD4+ T cells (c), CD4+/IFN-γ+ T cells (d), CD8+ T cells (e), and CD8+/IFN-γ+ T cells (f) in cell suspensions prepared from the lungs isolated from Fas (−), FasL (−), and WT (C57BL/6) mice at 3, 7, 10, and 14 days of ECTV infection and from control, uninfected mice. The bars represent the mean from 5 separate experiments ± SEM. Significant differences with and in comparison to Fas- and FasL-deficient mice.

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