Hydrogen-Rich Saline Protects against Ischemia/Reperfusion Injury in Grafts after Pancreas Transplantations by Reducing Oxidative Stress in Rats

Figure 4

Pancreatic tissue levels of MDA, SOD, and GPx in rats exposed to various treatments. After I/R injury, the MDA level (a) in pancreatic tissue presented a pronounced increase, and the SOD (b) and GPx (c) in the pancreas were nearly depleted. The administration of hydrogen-rich saline (0.6 mM, 6 mL/kg) effectively improved the SOD and GPx levels in the pancreas with significantly reduced pancreatic MDA levels. compared with the SO group; compared with the HPT + NS group.

(a)

(b)

(c)