ISU201 Enhances the Resolution of Airway Inflammation in a Mouse Model of an Acute Exacerbation of Asthma

Figure 2

Effects of drug treatment when administered after an exacerbation of experimental asthma on (a) neutrophils in lavage fluid (b) eosinophils in lung tissue, assessed by colorimetric assay for EPO. Animals were treated with vehicle (—●—), ISU201 (- -□- -), or dexamethasone (⋯○⋯) at 2 and 8 hours after induction of an exacerbation. Data are mean ± SEM ( animals per group). Significant differences relative to vehicle-treated animals at each time point are shown as () and ().

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